House and Cuddy board a flight back to the United States from Singapore, where a violent illness is spreading among passengers on the flight, putting their own lives in danger.
The Davids and the Blacks move into a new house, and take in a new guest; Larry rewrites a dry-cleaning rule; Jeff finds his reputation stained; Larry envies Ted's anonymity.
Michael hires a woman who turns out to be his long-lost sister, Nellie, and who may be just what the company needs.