Erin's case against cartel member Carlos Munoz intersects with a husband-and-wife domestic abuse call that Jamie handled, but when the wife is murdered all hands are on deck, the husband becomes the prime suspect.
Danny and Baez respond to a call that their psychic friend, Maggie Gibson, has been stabbed.
Reagan family tensions run high when Frank and his grandson, Joe Hill (Will Hochman), contend with a grievous insult to the memory of Joe's father, Joe Reagan.
Danny crosses paths with Sonny Le (Alex Duong), a criminal from a previous case, when he investigates a gang attack with a shocking motive.
Jamie and his new intel team officer infiltrate a high-tech car smuggling ring. Also, Frank faces off against the city's transit chief over a new mayoral solo police patrol program that is causing officer injuries on the job.