New Amsterdam is still reeling from the pandemic as a plane crash lands in the East River. When investigators come to interrogate the flight crew, Iggy fights against the clock to help the pilot uncover the truth. Max tracks down scarce medication after one of his own contracts COVID.
Max discovers a revenue-generating department at the hospital that has serious legal implications. Iggy discovers a janitor with otherworldly talents. Reynolds treats a truly inspirational patient and makes plans for his father. Wilder’s young patient teaches her not to jump to conclusions in diagnosing.
Max and Sharpe wake up to a new, more personal dynamic. Iggy calls upon an old contact to help with an explosive situation at the hospital. Bloom begins a tricky dynamic with her new Emergency Department residents. Reynolds finds himself in an awkward position with Dr. Baptiste and his wife, Dr. Lyn Malvo.
Max is on a mission to fix systemic racism at New Amsterdam. Bloom treats a patient who reminds her that things aren’t as they seem. Sharpe is overwhelmed while tending to a family matter. Reynolds tries to keep his composure while treating a father and son.
When an inmate comes in with an entirely preventable illness, Max, Sharpe, and Iggy head directly to the source - Rikers Island. Meanwhile, Bloom struggles with her recovery, and Reynolds gets news that could change his life.