Bull takes on the trial defense of Dr. Natalie Reznick (Brooke Bloom), an expert on anthrax, who is accused of orchestrating a series of anthrax attacks that terrorize the city. While the facts are against her, Bull sets out to prove the city was in such a rush to get the bacteria off the streets and calm the public�s hysteria, they arrested the wrong person.
Tommy works to keep her officers in line when one of their own turns up dead, and some want to take extreme measures to find the perpetrator. Also, Mayor Buddy Gray and Deputy Mayor Doug Dudik are concerned about what damaging information Arturo Lopez (Arturo Del Puerto), a recently arrested acquaintance of Buddy's, may have on him.
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