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Princeton-Plainsboro Teaching Hospital is turned upside-down when billionaire entrepreneur Edward Vogler (guest star Chi McBride) buys his way into becoming Chairman of the Board. Vogler intends to use the hospital as a new biotech venture, meaning they no longer require the financially draining services of one Dr. Gregory House. Meanwhile, a powerful young woman who seemingly has it all (guest star Sarah Clarke) - perfect life, perfect body, perfect job - becomes inexplicably paralyzed. Upon discovering her deadly secret, House finds himself fighting for her life even though it means risking his job and his medical license.
