Sean Walker (Jason Ritter) stumbles into a national conspiracy after his girlfriend Leila (Sarah Roemer) mysteriously disappears from a Caribbean cruise. Elsewhere, President Elias Martinez (Blair Underwood) is scheduled to announce the release of a group of detainees led by Sophia Maguire (Laura Innes) -- despite the disapproval of his Director of National Intelligence, Blake Sterling (Zeljko Ivanek). Their futures are on a collision course in a global conspiracy that could ultimately change the fate of mankind. Scott Patterson, Ian Anthony Dale, Clifton Collins, Jr., Taylor Cole, Lisa Vidal and Bill Smitrovich also star in the ensemble drama. Tony Todd, Lauren Stamile, Julia Campbell, Gonzalo Menendez, Joseph C. Phillips, Casey Siemaszko, Omid Abtahi, Angel Desai, Wynn Everett, Michael Cummings, Lorena Segura York, and Wes Ramsey guest star. Directed by Jeffrey Reiner.

As the shockwave of the plane dissipates, President Martinez's (Blair Underwood) staff must work quickly to assess what happened and how to respond. Director of National Intelligence, Blake Sterling, (Zeljko Ivanek) locks down Sophia (Laura Innes) for interrogation. The conspiracy widens, engulfing FBI Agent Collier (guest star Heather McComb) and Carter (guest star D. B. Sweeney), a mercenary with questionable ties. Meanwhile, a shadowy figure, Thomas (Clifton Collins, Jr.), emerges with knowledge of the detainees and their plan.

President Martinez's (Blair Underwood) administration unveils a tough new strategy to force Sophia (Laura Innes) to reveal the detainees' plan, putting into play a new detainee, Maya (guest star Clea DuVall). Elsewhere, we learn that Vicky (Taylor Cole) and Carter (guest star D. B. Sweeney) are in possession of a crucial hostage. FBI Agent Collier's (guest star Heather McComb) suspicion grows deeper.

The White House grapples with a mysterious biological threat. Their only hope is to crack Sophia (Laura Innes) during interrogation. Meanwhile, Vicky (Taylor Cole) and Carter (guest star D.B. Sweeney) keep their hostage captive while they await further instructions. FBI Agent Collier (guest star Heather McComb), on her search for Leila (Sarah Roemer), stumbles upon Vicky's secret life. Elsewhere, a powerful businessman, Dempsey (guest star Hal Holbrook) with classified intelligence and ties to the White House, emerges from the shadows. Jason Ritter, Blair Underwood, Željko Ivanek, Clifton Collins, Jr., Ian Anthony Dale, Scott Patterson, Lisa Vidal, and Bill Smitrovich. Directed by: John Badham.

The biological threat intensifies. The CDC rushes to identify the contagion and treat the infected people, while the White House and Director of National Intelligence (Zeljko Ivanek) face a difficult dilemma in their negotiation with Thomas (Clifton Collins, Jr.). Meanwhile, Simon (Ian Anthony Dale) appeals to Sophia (Laura Innes) to turn on Thomas. Elsewhere, FBI Agent Collier (guest star Heather McComb) closes in on Vicky (Taylor Cole) and Carter (guest star D.B. Sweeney), but appearances are not always what they seem. Jason Ritter, Sarah Roemer, Blair Underwood, Scott Patterson, Lisa Vidal, and Bill Smitrovich. Directed by: Milan Cheylov.

President Martinez (Blair Underwood) and the Director of National Intelligence, Blake Sterling (Zeljko Ivanek), fulfill their agreement with Thomas (Clifton Collins, Jr.), but after their plan goes awry, they suspect that there is a possible mole in their midst. Elsewhere, Sean Walker (Jason Ritter) digs for answers at Leila's home, where he encounters Madeline (guest star Paula Malcomson), a mysterious conspiracy theorist. Meanwhile, Simon's (Ian Anthony Dale) past is illuminated, and his allegiances are tested. Sarah Roemer, Laura Innes, Scott Patterson, Lisa Vidal and Bill Smitrovich also star. Directed by: Jonas Pate.