One of the most-wanted fugitives in the country turns himself in - under one condition: He'll only speak with newly minted profiler Elizabeth Keen.

Red (James Spader) offers to turn over an elusive assassin whose next target is a high-profile anti-human-trafficking activist. Liz (Megan Boone) learns a troubling secret about her comatose husband. Guest starring Isabella Rossellini and Jane Alexander.

Red (James Spader) takes Liz (Megan Boone) on an undercover assignment to bring down a freelance Chinese spy who’s targeting CIA agents.

When a witness in the murder trial of a ruthless cartel boss disappears, Red (James Spader) leads Liz (Megan Boone) and Ressler (Diego Klattenhoff) on a search for the Blacklist’s No. 161, a gruesome hit man known as the Stewmaker.

Red (James Spader) leads Liz (Megan Boone) and Ressler (Diego Klattenhoff) in a hunt for a kidnap victim and his abductor – The Blacklist No. 85, a secretive criminal courier whose inability to feel pain makes him impossible to stop. Liz uncovers evidence linking Tom (Ryan Eggold) to a Russian defector’s unsolved murder.

Liz’s (Megan Boone) search for corporate terrorist Gina Zanetakos (guest star Margarita Levieva) – Blacklist No. 152 – exposes a plot to detonate a radioactive bomb and uncovers evidence linking Tom (Ryan Eggold) to the murder of a Russian defector.