On the run after the end of Season 3, an injured June (Elisabeth Moss) and the fugitive Handmaids find refuge at a farm, where the 14-year-old Wife nurses June back to health. June restores her role as the women’s leader. In Gilead, an imprisoned Lawrence (Bradley Whitford) tries to avoid a death sentence, and Aunt Lydia (Ann Dowd) reels from the loss of 86 children on Angels’ Flight. The combative Waterfords (Joseph Fiennes, Yvonne Strahovski), in custody in Toronto, learn of June’s feat.
June (Elisabeth Moss) plots revenge at the local Jezebels, before she and the Handmaids plan to leave the farm for the next safe house. Meanwhile, in Toronto, Moira (Samira Wiley) deals with the fallout of June’s choices, and Serena (Yvonne Strahovski) and Fred (Joseph Fiennes) are bound together by a miracle.
Captured by Gilead, June (Elisabeth Moss) faces a vengeful Aunt Lydia (Ann Dowd) and endures a torturous interrogation. Nick (Max Minghella) and Lawrence (Bradley Whitford) collaborate to protect June. Meanwhile, in Toronto, Luke (O-T Fagbenle) struggles with how to help June and Hannah.
June (Elisabeth Moss) takes a harrowing journey with Janine (Madeline Brewer), trying to escape Gilead, as Janine remembers a stressful experience in her past. In Toronto, Serena (Yvonne Strahovski) tries to manipulate Rita (Amanda Brugel), who seeks advice from Moira (Samira Wiley).
June (Elisabeth Moss) seeks out more active rebels in the Chicago war zone, while Janine (Madeline Brewer) tries to help her fit in with their new group of survivors. Meanwhile, Moira (Samira Wiley) goes on her first field aid mission.
After a shocking reunion with a dear friend, June (Elisabeth Moss) contemplates the possibility of freedom and confronts the unfulfilled promises she’s made to herself and to Luke (O-T Fagbenle).
Elisabeth Moss
Offred/June
Joseph Fiennes
Commander Waterford
Yvonne Strahovski
Serena Joy
Samira Wiley
Moira
Alexis Bledel
Ofglen/Emily