Emmy winner Carl Betz and Barbara Anderson, and Robert Conrad are the guest stars as Jim Phelps, with the aid of Barney's electronic wizardry, takes in the guise of a hot-shot pool hustler to break up an illegal gambling operation.
Vic Morrow guest stars as Joe Collins, a nuclear scientist who is made to believe that he is a prisoner in the year 2000 and is about to be executed as part of the IMF's plans to learn where he has hidden enough plutonium to construct a dozen atomic bombs.
Robert Webber guest stars as Charles Rogan, a syndicate leader with the key to the five million dollar bankroll that will finance the overthrow the government of Camagua.
Robert Goulet guest stars as Joe Epic, a syndicate crime leader and key figure in an IMF plan to free a captured undercover agent.
To locate a terrorist ring called Alpha Group, the IMF convinces turncoat intelligence agent Gordon Holt, played by guest star Peter Haskell, that he's been exposed to the stolen biological weapon he's been hired to deliver.
William Shatner guest stars as Joe Conrad, a drug dealer who becomes the unwitting dupe of the Impossible Missions Force in their plan to capture the largest shipment of cocaine ever brought into the country.
Leonard Nimoy
Paris
Steven Hill
Daniel Briggs
Peter Graves
James Phelps
Martin Landau
Rollin Hand
Barbara Bain
Cinnamon Carter