CIA and political experts scrutinize historical events surrounding the assassination, including the 1960 presidential campaign, an attempted coup on Guatemala, and The Bay of Pigs. Meanwhile, the Secret Service is hot on Lee Harvey Oswald's heels.

Understanding JFK's political career and Lee Harvey Oswald's movements allows for a deeper dive into the conspiracy surrounding the Mafia and their connection to Robert Kennedy. Kennedy's crackdown on organized crime may have influenced the Chicago outfit and Fidel Castro.