After hitting a wall in his case against drug kingpin Ernesto Mendoza (Andrew Divoff), private eye Andre Shame (Keenen Ivory Wayans) quits the police department in disgrace. The wisecracking investigator thinks he's left his old life behind him, but now everything changes when an old chum from the force informs him of a break in the case. With the help of his motor-mouthed secretary, Peaches (Jada Pinkett), Andre leaps back into the action to solve the case and clear his name.