Barney and Ted consider making a life-altering decision together; Robin tries to talk Lily and Marshall out of moving to Long Island.
Conrad finds himself caught between his duties as a doctor and his loyalty to Kit when he discovers that her son-in-law may be suffering from a serious disease; Devon and Nic make a shocking discovery about a former patient.
Just when Derek's condition seems to be improving, a severe complication arises; when Cain's former girlfriend is admitted to the hospital for surgery, the doctors finally get a glimpse into his personal life.
Cain recruits Ezra to help keep an emergency situation under wraps; Nic works to come up with a support system for a patient in need of a lung transplant; Kit's son-in-law's condition continues to worsen.