Helldriver

An alien-spawned, mysterious mist blankets the northern half of Japan, transforming those who inhale it into ravenous, flesh-eating zombies. Hope arrives in the form of Kika (Yumiko Hara), a beautiful high school girl armed with a chainsaw sword powered by an artificial heart. Recruited by the government, Kika leads a ragtag group of desperados on a secret mission into the zombie-infected wilds to exterminate zombie queen Rikka (Eihi Shiina from Audition and Tokyo Gore Police) and put an end to the plague of the living dead. But the road is fraught with a thriving zombie population that refuses to lay down and die!