The CBI team investigates the kidnapping of a couple (guest stars ANNE DUDEK and MICHAEL PETRONE) that may be the victim of mistaken identity, while Jane continues his investigation into Lorelei’s whereabouts.
Symptoms point to a possible genetic connection when House notices something about the son of a man (John Larroquette) who has been in a coma for a decade; Wilson confronts House about stealing his prescription pad.
Melinda investigates the death of a high school athlete whose ghost is following around a family that is not her own.
J.D. Turk Denise and Drs. Kelso and Cox teach med school at Sacred Heart; med students Drew Lucy Maya and Cole attend their first day of school.