The special Federal Bureau of Investigation Missing Persons Squad's sole responsibility is to find missing people by applying advanced psychological profiling to reveal the victims' lives.
Jack and his team search for an 11-year-old boy, Gabe, who disappears from a subway station en route to Yankee Stadium for what was to be his birthday celebration.
As a couple cross to their car after a day of shopping, Duncan realizes that he needs to go back into the store to retrieve his credit card. After Duncan walks away, his wife's car speeds off, leaving a bystander injured.
The agents' job is harder than usual because they must find a woman, who changes her appearance to suit whatever modeling or acting job she is seeking at the time.
Jack and his squad search for a young man, 17-year-old, who was last seen by the charismatic headmaster of Spalding Academy.
Jack and the team search for a New York businessman, who disappears after he checks in for a routine airline flight home.
Anthony LaPaglia
Special Agent Jack Malone
Poppy Montgomery
Special Agent Samantha Spade
Marianne Jean-Baptiste
Special Agent Vivian Johnson
Enrique Murciano
Special Agent Danny Taylor
Eric Close
Special Agent Martin Fitzgerald