Rosalba (Licia Maglietta), a middle-aged woman on a bus trip to Venice with her husband and her sons, is left behind at a rest stop off of the highway. As the days go by with no word from her family, she settles into a room at a local hotel and takes a job at a flower shop. When her husband and sons begin to miss her, they send a friend looking for her. "Bread and Tulips" is a warmhearted comedy about love, family, and friendship.