Different Drummers is a deeply inspirational family film - based on a true story - about an unusual spiritual journey and unlikely friendship from 1965. David (11), wheelchair-bound by muscular dystrophy, is growing weaker, while Lyle (10), has a problem with an increasingly high energy level. David informs Lyle that their teacher is about to die and states that God told him. When his prediction comes true, a confused Lyle feels he must find out for certain if God exists. Lyle convinces David that he can teach him to run, secretly viewing this as a way to test the existence of God. Lyle's question is ultimately answered, in a way he never could have imagined.