Dr Reid investigates a decades-old murder that happened in Las Vegas that he thinks is connected to his own childhood.
Barney tries to prove Ted wrong by completing every task on Ted's list of things he thinks the gang is too old to do.
Sue manages to get into an R-rated movie; Frankie tries to find a friend for Brick; Axl's band looks for a woman to feature in their music video.
Neela must testify in court after a patient's death; Alex and Sarah have a car accident; Morris and Banfield are snowed in at an ER conference.
The Darlings prepare for Ellen's memorial service; Nola Lyon's real profession comes to light; Lisa and Nick discuss about having another child; Letitia's trial begins; the arrest of a suspect in Dutch's murder stirs up the Darlings.