The BAU is out on the hunt for a Boston killer who keeps a memento from each victim. Meanwhile, Rossi tries to stop his favourite bar from closing down.
Jealousy abounds among the team when a young computer specialist helps investigate the hijacking of a missile test.
Jane holds a smoking gun, having shot dead the man he believes to be his nemesis, the serial killer Red John.
Gabrielle and Carlos host Carmen, Hector, and Grace for a Thanksgiving feast. However, the Solises discover some surprising news about the Sanchezes that could threaten their time with Grace.
The team investigate when a wealthy woman suffering from terminal cancer is murdered only moments before she planned to commit suicide.