After Dr Sturgis experiences a nervous breakdown, Mary worries Sheldon is headed down a similar path; Georgie discovers he has a knack for sales.
While undergoing aggressive cancer treatment, Izzie focuses on planning Meredith and Derek's wedding; Callie's father visits; Owen seeks help with his PTSD.
Lily and Ted argue after Lily hears an old message from Ted on Marshall's answering machine encouraging him to recall Lily's bad points and calling her a grinch.
Thanksgiving plans are put on hold while the team investigate the horrific death of a Marine.
A military family come under suspicion when a boy finds a murder weapon and the team must track ownership of the gun.