While on Air Force One, a Navy Commander dies. Agents from the Navy NCIS decide to take the investigation into their own hands and force Secret Service Agent Kate Todd to help. The NCIS team then has to figure out if the Navy Officer's death was of natural causes or not.
The shooting investigation of Holly Gribbs continues; someone is murdering people who have won millions on slot machines.
A murder suspect is caught burying the bodies of his alleged victims; Catherine and Warrick investigate a woman found dead in a hotel's spa.
Grissom and Catherine follow leads from a young woman's death into the underground world of Las Vegas fetish clubs.
A correlation is drawn between two crimes when two people are shot during a casino heist and Catherine and Sara are called to a murder in the desert.