After several of Bailey's patients die, she becomes the focus of a CDC investigation; Cristina teases Alex about his feelings for Jo; Owen continues to take care of Ethan while his parents remain in the hospital.
The death of a woman found mummified in a wine cellar is investigated, while a recuperating Jane receives devastating news.
Korsak tries to help an old friend fulfil his dying wish: to finally solve the deaths of his wife and daughter in a house fire some 15 years earlier.
A man's body is found in a bathtub, and the investigation reveals that not only was he strangled to death, but he was also a millionaire.
Castle is abducted and subjected to a humiliating series of mind games and puzzles; Beckett and the precinct work desperately to recover Castle and unveil a murderer.