Meredith's fears of a bad day are realised when a medical case threatens the lives of everyone in the OR; Izzie decides to take things further with Alex.
Despite the best efforts of the Seattle Grace staff, the code black situation escalates; Bailey's distress puts her unborn baby at risk.
The BAU team begin to track a family in Alabama who are working together to abduct young women. The family travel from city to city leaving clues behind, but their route becomes increasingly difficult to follow.
Teresa believes an argument between lovers led to the murder of a woman in a Napa Valley vineyard. Patrick, on the other hand, pursues his own investigation with Grace being used as bait.
A widowed Wyoming sheriff works to overcome the pain of his wife's death by dedicating himself to his job.