The team head to Kansas City where they look into a report of homeless people vanishing from the city's streets.
Grissom and Sarah investigate the murder of a mental-hospital patient and quickly narrow the suspects to several patients and staff members.
House and Cameron explore their relationship; the team try to uncover the cause of a young man's blood clots and strokes.
Harm and Meg have a courtroom showdown over child custody when Harm represents an AWOL Marine who disappears with his young son.
An anxiously anticipated letter reveals how Rebecca has been spending her time after work; Bobby seeks approval from his father.