Meredith's fears of a bad day are realised when a medical case threatens the lives of everyone in the OR; Izzie decides to take things further with Alex.
When a dead staff sergeant is found encased in a Civil War-era tomb, a cell phone within it leads investigators to a safety deposit box.
A serial killer in Rhode Island is spreading panic by attacking victims in public.
The sister of Booth's detective friend, Ken, goes missing. When the decapitated head is found, Ken joins Brennan and Booth to help solve her murder.
Dr Foreman suspects a homeless woman is faking seizures to stay in the hospital. However, her worsening condition confuses Dr House and his team.