As Nathan and Jamie join Haley for the last stretch of her tour, Brooke and Julian are reunited after their break. Alex emerges from rehab and tries to make amends with the people she hurt and disappointed.
Nathan struggles to reach an increasingly despondent Haley; Quinn leads Jamie on a Tree Hill treasure hunt; Julian shows his finished film to Brooke; Clay is forced to deal with a deranged Katie.
When Lydia's condition worsens, Haley and Quinn decide to try and reconnect with Taylor; Nathan continues to help Jamie come to terms with Lydia's impending death.
Haley and Jamie struggle to accept Lydia's seemingly hopeless situation, leading Nathan to try and help them come to terms with it; Clay and Quinn spend some time apart.
On the eve of Quinn's big gallery opening, an uninvited guest ambushes Clay; Nathan spends the day with Jamie; Haley struggles with life after her mother's passing.