Noelle McCutchen

First-year surgical intern Meredith Grey begins her first day in the demanding residency program at Seattle Grace Hospital.

Meredith attempts to work with Addison Shepher; Cristina ponders her relationship with Burke; Meredith is devastated by the latest blow to her love life.

Meredith fights to keep her emotions in check when a secret about her mother is revealed; Alex and Izzie grow close.

Cristina is revealed to be a difficult patient as she recovers; Meredith's mother has the staff running in circles.

Bailey interferes in Meredith and Derek's relationship. Alex works hard to gain the trust of a shy patient with a gargantuan tumour.

Izzie grills George; Addison takes Alex to task on a sensitive case; Burke feels the pressure when he treats his musical hero.