Regi Davis

While undergoing aggressive cancer treatment, Izzie focuses on planning Meredith and Derek's wedding; Callie's father visits; Owen seeks help with his PTSD.

All reassess their personal lives after witnessing a chance reunion between two long-lost lovers in the emergency room; Karev treats a troubled teen; Meredith shares her suspicions with Cristina.

Prentiss resigns, Hotch requests a transfer and Gideon goes missing, leaving the team three members short as they hunt a serial killer in Milwaukee, who kidnaps women from public places.

Gibbs and McGee travel to Russia to safely escort home an NCIS computer engineer connected to classified intel, but their mission is compromised and they are forced to go off the grid while hunted by a Russian mercenary group.

The gang heads to the Caribbean, where Frasier begins to question his new romance with Claire.

Lilly decides to hold a sale to raise money for her class trip to Washington. Hannah tries to lend a hand and hires people to buy stuff.