MacGyver matches wits with a corrupt military force, when he attempts to save a photojournalist from a South American crime syndicate.
The detectives don't believe that the shooting of a cop with an active night life is as random as he claims; Rodriguez uses old connections to get a confession from a suspect.
Dr Benton struggles with his new role as a parent; Dr Carter has trouble with a new medical student; Dr Ross helps Dr Del Amico examine a young athlete.
On Christmas Eve, Dr Benton and Dr Del Amico treat a blind patient, and Hathaway gives a tour of her clinic to Dr Carter's grandmother.
Dr Del Amico's old boyfriend arrives at the hospital to conduct a study. Meanwhile, a televangelist uses her illness and the ER for financial gain.