Sarah Utterback

When a family arrives at Seattle Grace Hospital after a serious car accident, Alex learns that their injuries are only the beginning of their problems.

A sexually transmitted disease infects several members of hospital staff. Izzie and Cristina worry about a patient whose wife and daughter are at odds over his care. A bombshell is dropped just as Meredith and Derek grow closer.

Derek and Meredith try to be discreet after spending the night together at her house. George suspects an anaesthesiologist is drinking while at work.

Izzie copes with the loss of Denny and her decision to leave the internship program; Meredith faces decisions about her future after her liaison with Derek.

Meredith is mortified when her one night stand shows up at the hospital suffering from a priapism; a woman carrying quintuplets is overwhelmed by numerous medical issues; Izzie is frustrated by Alex's shortcomings.

Meredith's fears of a bad day are realised when a medical case threatens the lives of everyone in the OR; Izzie decides to take things further with Alex.