Omar continues his bold strikes on Barksdale stash houses. As the wire on east Baltimore's Proposition Joe continues to yield little, a restless McNulty launches his own reinvestigation of D'Angelo Barksdale's prison suicide.
Bunk and Freamon chase a container ship that is a crime scene to Philadelphia, Lt Cedric Daniels is unhappy with his assignment, and McNulty pursues the identity of his Jane Doe.
Ziggy loses his prized Camaro to drug dealers who aren't buying his excuses about not paying up. Unable to dump the homicide investigation on other police agencies, Col Rawls identifies Det Moreland for the blame if the cases go unsolved.
When a witness who testified against D'Angelo Barksdale is discovered murdered, McNulty and the detail take the opportunity to link the killing to Avon Barksdale's drugs crew.
Sobotka sees an unwelcomed future at the port of Rotterdam, and gives his lobbyist grief over the status of port legislation. Russell tells Sobotka the investigation is over.