The murder of a high rolling investor is investigated by Danny and Jackie. Meanwhile, Frank puts Jamie under house arrest when the Sanfinos put out a hit.
Alicia and Will must decide whether to cooperate with each other when they each represent one half of a couple accused of smuggling drugs. Further, two juries are appointed to hear the evidence simultaneously.
Dominic begins to enact Madeline's cataclysmic scheme as the team rushes to stop him. Meanwhile, tensions rise between all of them as past secrets begin to unravel.
Laurel finds out how to drive the bugs out of a person's brain, and uses this to remove the Queen bug from Red's head.
When a Marine is accused of helping a terrorist escape from Guantanamo Bay, Abe and Harper believe that they have an open-and-shut case, until they are mysteriously denied access to key evidence without explanation.