Wayne Lopez

Izzie copes with the loss of Denny and her decision to leave the internship program; Meredith faces decisions about her future after her liaison with Derek.

A series of deaths at the hospital brings out the superstitious side of the doctors and makes Izzie nervous about Denny's surgery; Derek and Addison discuss living arrangements; Richard treats an old friend.

Robin, desperate to find a job before she is deported, agrees to let Barney produce a video resume for her.

The interns deal with a family involved in a car accident and Derek lets his emotions get the best of him; Burke and Izzie make a suggestion to Denny.

Derek and Meredith get ready for their wedding; college students injured in a car accident are admitted to the ER; Izzie starts experiencing familiar symptoms.

After a petty officer's son is found murdered, evidence suggests Kasie's lifelong best friend is guilty.