Derek decides to quit after learning that more of his patients have died than survived; Izzie's interns make an unsettling discovery about Patient X.
The BAU head to Miami to investigate a serial killer with a seemingly conflicted sexual identity. JJ reconnects with a former colleague and a secret is revealed.
Carrie thinks she likes being single, Miranda fakes an orgasm, and Samantha likes a nightclub owner.
Baez and Danny search desperately for a missing girl who'll die without her heart medication; Eddie and Jamie engage in a car chase and end up on the wrong side of an investigation; Sean wins an essay contest.
When a student goes missing during a school excursion to New York City, the cops attempt to hunt down a mysterious masked man.
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