Seven-year-old Jack is undergoing his 22nd operation. Jack has a range of genetic conditions, which led to him having both of his kidneys removed.

One-year-old Charlie, who is profoundly deaf, undergoes a ground-breaking implant operation to restore his hearing. Professor Richard Ramsden comes out of retirement to perform this pioneering five-hour surgery.

Fourteen-year-old DJ Lockley has lived on a kidney machine for nine hours a day, six days a week for six months. He needs a new kidney, which his mother has agreed to donate, but there is a risk his body could reject it.

Follow the work of staff and progress of kids at the Royal Manchester Children's Hospital, now the largest hospital for children in the UK.

Six-year-old Emily Fish has a rare blood disorder and needs a bone marrow transplant, but it will require weeks of gruelling chemotherapy.

After undergoing 22 operations, seven-year-old Jack Norfolk finds out if he needs more surgery; a youngster who has broken his wrist in every place possible receives treatment.