The doctors see some jaw-dropping sights, including Glenn whose stomach oedema literally touches the floor, and successful slimmer Julia whose new slim frame is draped in excess skin.

Dr Christian meets a couple with a combined weight of 330 kg whose lives depend on bariatric surgery; Dr Pixie consults with a 21-year-old mother whose enormous J cup breasts are interfering with her life.

The doctors meet a teenager once dubbed UK's fattest teenager who became the youngest person ever to undergo gastric banding. Then, they investigate how fat can cause permanent joint damage.

The doctors deal with the impact obesity has on fertility, the largest man boobs Dr Pixie has ever seen and excess hair caused by polycystic ovaries.

This episode revisits some of the most memorable and impactful cases from the show's history. Dr. Dawn and Dr. Pixie McKenna travel to Glasgow, one of the world's fattest cities, to see how patients have fared since their initial consultations

Dr Christian continues the story of Patience, a woman whose excessive eating left her with a growth on her leg the weight of a small child.