Teenager Sho Fukamachi's life is changed forever when he discovers a mysterious Guyver unit, which he accidentally activates.

Sho uses the Guyver unit to protect his friend from imminent danger and to battle two Zoanoids. Plus, the final Guyver unit finally merges with Inspector Risker.

Sho finally takes a chance and faces off against Lisker and Zoanoid soldiers. Plus, Chronos sends an entire troop of Zoanoids to apprehend Sho.

Sho must activate the Guyver unit and fend off more Zoanoids, before the rest of the gang is put in imminent danger.

Genzo Makashima, ex-head of Cronos Japan and Agito Makashima's foster father, is punished by being processed as a Zoanoid.

Guyot introduces ENZYME and reveals his devious plan to capture Guyver I, in order to save the gang from imminent danger.