Lestrade and Holmes try to track a villain.

Holmes, Watson and Lestrade discover a makeshift lab where Fenwick is turning ordinary citizens into criminals.

A giant hound has been seen on the moon and people are worried. It's up to Holmes, Watson and Lestrade to investigate what's happening and to catch who's responsible for it all.

Using DNA washer, Holmes transforms himself into the likeness of Dr. Blessington to free the world of Moriarty.

Sherlock Holmes deals with animal rights when the owner of a failing zoo becomes a mutated man-snake in order to steal valuable nanobot technology and saving his failing zoo.

Holmes investigates the poisoning of Joseph Openshaw.