When the Venture family visits Tijuana so that Dr Venture can give a lecture at the University of Mexico, The Monarch weaves a cocoon of villainy that leaves the Venture Brothers trapped, Dr Venture kidney-less and Brock, dead?

They are soon put to the test when The Monarch and Baron Underbheit send their henchmen to attack on the same night.

The Venture family become trapped in Dr Venture's latest invention and the only one who can save them is new neighbour, master of mysticism, Dr Orpheus.

On a scientific expedition in the Bermuda Triangle, Dr Venture disturbs the spirit of a test pilot who crashed an experimental aircraft designed by the Dr's father.