CIA hit-man Al Simmons's death causes him to seal a deal with the Devil so that he can return to his wife, Wanda; however, the Devil transforms him into hell spawn.

Peeved at the death of his three henchmen, mob boss Tony Twist sends a new trio to the alley. They soon return with a warning from Spawn: for Twist to stay away.

When a hired cyborg named Overkill engages Spawn in battle, Spawn is forced to steal some of Al Simmons' old weapons from a guarded CIA munitions compound.

Tony Twist sends an underling named Castellano to Rome to apologise for Overkill's death; Wanda goes to the park to meet Max, a private investigator.

Spawn is forced to intervene when a grenade-toting preacher takes a mute boy hostage and threatens to kill anyone who gets in his way.

Spawn uncovers the truth about his identity as the kidnapping of Wanda's daughter edges him toward a showdown with Billy.