Candice Afia

Bailey and a team of surgeons must remove a young girl's inoperable tumor; as the new head of trauma, Owen Hunt challenges the surgical abilities of the residents and the attending doctor's methods.

The residents and interns treat the victims of a massive explosion at an apartment building; Mama Burke returns to collect her son's things; Lexie tries to have a heart-to-heart with unwilling Meredith.

An ambulance crash endangers the lives of the paramedics involved; Bailey treats a patient who refuses her help; Ava returns for Alex and meets his other girlfriend.

Bailey and Seattle Grace's new pediatric surgeon try to save the life of a longtime patient; the admission of a death row inmate angers Derek; Izzie tells Alex that she has been seeing Denny.

Cristina, back from her honeymoon trip, searches in vain for Burke; Meredith, Cristina, Izzie and Alex spend their first day as residents with their own groups of interns.

Derek's mother makes a surprise visit and meets Meredith for the first time; Mark tries to hide his relationship with Lexie; Cristina and Owen try to go on their first date.