The O'Malley family visits George at the hospital; Meredith determines to have a more positive outlook on life; Derek and Addison strive for a civil relationship; Richard endeavors to reunite with his wife, Adele.
A traumatic car accident fills the ER; Cristina has a crisis of conscience about her deceptive teamwork with Burke; Izzie pushes the boundaries of probation.
The men of Seattle Grace go on a camping trip; Addison and Callie must team up to work on a patient; Meredith assists with a procedure Sloan has never experienced; Bailey confronts Cristina, suspicious of her recent actions.
Recent events strain Burke and Cristina's relationship; Meredith's half sister enters the hospital; Mark and Derek must work together when two close-knit brothers seek medical help.
George's father has surgery for his cancer; Thatcher Grey arrives to see his new granddaughter; Meredith finds that Derek has trouble sleeping.
