Nolan deals with a skeleton from his past; Daniel's role is challenged; Carl's christening reveals new concerns for Jack and Declan.
JD questions the bond he has with his interns when Dr Kelso tells him that inevitably he will begin treating them badly, as it has been throughout history at the hospital. The Janitor further complicates matters by telling JD that his interns only laugh at his jokes to suck up to him. Meanwhile, Carla visits Elliot at her new job and inadvertently creates an awkward new nickname for her friend.
When a homeless woman goes missing from a shelter linked to a previous case, Jack suspects Rick Knowles -one of two identical twins--who manipulated his brother, Greg, into confessing to the murders of several other homeless women.