Meredith and Cristina bicker about their careers; Bailey talks to Ben about him moving back to Seattle; Shane puts himself in a risky situation; Derek receives a life-changing phone call.
Bailey asks Richard to join her on the case of a lifetime; Meredith decides to hire a research assistant; Callie shocks Derek; a young pregnant woman (Keke Palmer) needs Shane's help.
Arizona's bad day escalates when she advises a patient on a potential double amputation; Derek breaks a promise; Stephanie and Jo find an abandoned baby; the nonfraternization rule leads to a suspension.
Cal is contacted by a pharmaceutical company when the formula of a potentially deadly drug is stolen. Is it an inside job or are there twists in the tale?
Jack loosens his control of Amador in an attempt to learn who he is working for; CTU quarantines an entire hotel where one of the vials with the virus has been planted.