The BAU tracks a con artist whose schemes have become so complicated that he begins to eliminate the people involved in them.
Sqweegel, a serial killer who is punishing local heroes that harbor hidden secrets, is on the hunt in Las Vegas.
Izzie grills George about the personal details of his life, Addison takes Alex to task about a sensitive case, and Burke feels the pressure when he treats his musical hero.
A normal day turns to chaos when all people on Earth black out for 2 minutes, 17 seconds and see events from their own futures.
Owen asks Nick to get the details of his wife's affair with Ikey; Eddie's secret could be the end of his planned business venture with Nick; Sam tries to come to terms with his mother's marriage.