House believes a patient's (Howard Hesseman) seizure was caused by an infection, but the man's sudden heart attack forces the team to change direction and opt for a heart transplant.
April and Dr. Halstead can't agree on how to treat a homeless alcoholic with a broken leg; Dr. Manning realizes her wedding ring has gone missing; two elderly women with the same symptoms are linked in a surprising way.
Lightman tries to prove that a brilliant and charming psychology graduate student is a psychopath; Torres and Loker investigate a UFO sighting.
The CSI team investigates two apparent corpses, only to find that the two men, though initially pronounced dead, come back to life.
An old adversary who's now a jockey ask Gus and Shawn why his horse never wins. The case takes a turn when the jockey dies on his horse in the middle of a race.
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