The team investigates a murder linked to a counterfeit diamond operation, but an illness forces Jane to direct his colleagues from the office as he recuperates. Meanwhile, Abbott is concerned that transgressions in his past could harm his wife's chance to obtain a prestigious job in Washington D.C.
Charlie contacts Sam and Dean after she finds the book of the dead -- which could help eliminate the mark of Cain; Castiel and Metatron look for Castiel's grace.
A Marine photographer goes missing before providing testimony in a highly publicized case; Abby helps a young homeless woman.
When a 15-year-old hacker compromises missions, Callen goes under cover at a prestigious high school.
Moretti tracks down a kidnapper; Pierce and Moretti find out that there may be a child who needs their help; Donnie considers buying a house in the suburbs.