The BAU agents search for one of the most notorious serial killers in New England, who strikes again after a 10-year hiatus.
House shares explicit medical stories with students at a school's career day; two fifth-graders try to help House understand how his antics prevent him from showing Cuddy how he feels.
Keith has a problem with David's wish to become a deacon; Nate has dinner with Brenda's parents and meets her brother Billy.
A Los Angeles trouble shooter is called in to solve problems of the city's elite.
Peggy discovers the shocking truth about Leviathan but doesn't realize that her true enemies are even closer than she imagined.