Brennan and Booth travel to Mexico to investigate human remains with extraterrestrial attributes; Angela and intern Wendell come clean about their relationship.
Castle is captured and forced to work with strangers to solve deranged puzzles and mind games, while Beckett races to rescue him.
When a homeless teenager's (Bridgit Mendler) symptoms get worse, adult consent is required for an invasive surgery; Taub tries to connect with his daughters; House threatens Foreman's relationship with a married woman (Yaya DaCosta).
The team investigates the death of a petty officer and discovers he may have been leading a violent secret life.
Michael and Sam continue the hunt for Maxi's killer; Jesse, Fiona and Michael help a scientist recover a revolutionary formula from his greedy and duplicitous former business partner.
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