The BAU team races to help Hotchner find The Reaper and save his family before it's too late.
With help from her new ally, Emily seeks to destroy the district attorney who convicted her father; grieving Victoria tries to confirm her suspicions about Emily's past.
Callen and the NCIS: LA team confront their vengeful adversary, the Chameleon, when an undercover case ignites a deadly mind game orchestrated by the criminal mastermind.
Following Callen's public shooting of the Chameleon, all is not well with the NCIS: LA team, as Callen is placed on suspension and Hetty adjusts to retired life.
Izzie returns to work; Seattle Grace residents position themselves to avoid layoffs; Cristina tries to work with Arizona in the pediatric ward.